웹2015년 3월 20일 · The injurious effect of refluxed gastric acid, bile, pepsin, and duodenal contents on the normal protective mucosal barriers causes injury to the esophageal mucosa. 4 – 6 With ongoing reflux injury, surface esophageal cells die, triggering both an inflammatory response (infiltration of neutrophils) and a proliferative response (basal cell and papillary … 웹2016년 5월 5일 · The esophageal histologic abnormalities thought to be typical of GERD (basal cell hyperplasia, elongation of connective tissue papillae, infiltration by neutrophils and eosinophils) have been attributed to refluxed gastric acid-related chemical injury to esophageal epithelial cells starting at the luminal surface.
Eosinophilic esophagitis - Symptoms and causes
웹2016년 11월 15일 · A reactive (non-neoplastic) hyperplastic process affecting the esophageal squamous epithelium that is caused by inflammation. Morphologically it … 웹This has a high specificity for reflux disease as defined by ambulatory pH monitoring.16 Furthermore, basal cell hyperplasia and increased rete pegs are difficult to interpret in pinch biopsy specimens,17 with considerable intraobserver variation.18 We have therefore required the presence of intraepithelial polymorph leucocytes for a histological diagnosis of reflux … secretary department of biotechnology
Submucosal gland neoplasms of the esophagus: an …
웹2024년 1월 29일 · Also note the basal hyperplasia&emdash;the basal 12 layers are expanded from the 1 to 2 cell thickness expected in a normal esophagus. Figure 1.30 Moderate GERD. The easily identified … 웹2006년 12월 12일 · The mean intercellular space width was at least 2 times greater in patients than in controls, irrespective of esophageal acid exposure. Basal cell hyperplasia was observed in 9%–90% of patients compared with 10%–55% of controls. Papillary elongation was observed in 0%–85% of patients and 5%–20% of controls. 웹Download scientific diagram Distal esophageal squamous mucosa showing basal cell hyperplasia (>15% of the epithelial thickness) (black line) (Hematoxylin and eosin, x400). … puppy eyes open age