Ctck domain-containing protein

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WebMar 20, 2014 · VWF is a large (∼250 kDa) protein containing multiple domains (multicolored cylinders), including the CTCK domain (thin, light-colored disk) at one end … WebFurthermore, P-domains have been found as components of extracellular mosaic proteins including certain mucins, where they are thought to play a role either in protein-protein …

NLRP3 - Wikipedia

WebThe ACT domain is a structural motif in proteins of 70–80 amino acids that is one of a growing number of different intracellular small molecule binding domains that function in the control of metabolism, solute transport, and signal transduction (1–5). The first structure of an ACT domain was determined in 1995 with the crystal structure of Escherichia coli d-3 … WebTPR containing peptides Hop. The Hop adaptor protein mediates the association of the molecular chaperones Hsp70 and Hsp90. It contains three 3-TPR repeats each with its own peptide-binding specificity. Its TPR1 domain is known to recognize the C-terminal of Hsp70 while TPR2 binds to the C-terminal of Hsp90. grand turk scooter rental

Helical self-assembly of a mucin segment suggests an ... - PNAS

WebUniProt website fallback message If you are not seeing anything on this page, it might be for multiple reasons: You might have JavaScript disabled: make sure to ... WebAug 3, 2024 · Zinc-finger proteins, a superfamily of proteins with a typical structural domain that coordinates a zinc ion and binds nucleic acids, participate in the regulation … WebCARD domains are a subclass of protein motif known as the death fold, which features an arrangement of six to seven antiparallel alpha helices with a hydrophobic core and an outer face composed of charged residues. Other motifs in this class include the pyrin domain (PYD), death domain (DD), and death effector domain (DED), all of which also ... grand turk scuba

The Roles of CCCH Zinc-Finger Proteins in Plant Abiotic Stress ...

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WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … WebDec 13, 2000 · CARD4 (also called NOD1) is a CED-4/Apaf-1 family member that activates NF-κB signaling and induces apoptosis. 3,4,5 CARD4 contains three putative functional domains: an N-terminal CARD that ... grand turk shaw carpetWebThe protein mass of MUC2 residues 1398 to 4331 (the PTS region containing the CysD2 domain) is about 295,000 g/mol. Using the v for proteins of 0.73 cm 3 /g, the protein … grand turks getaway black necklace paparazzi

"WebJul 12, 2012 · The work described herein builds on early, significant work on the determination of the protein sequence, disulfide connectivity, cDNA sequence, and … " - Ctck domain-containing protein

Ctck domain-containing protein

The PYRIN domain: a novel motif found in apoptosis and inflammation ...

WebDec 21, 1999 · Blob diagram to illustrate various proteins containing IgSF domains, including the antigen receptors. The IgSF domains are illustrated by open circles and marked V, C1, or C2 according to sequence patterns and size . The lollipop symbols indicate the approximate position of N-linked glycosylation sites. The arrow in Thy-1 indicates the … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. …

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WebMay 26, 2024 · The TBC1D23 protein functions in membrane trafficking and is critical for human neuronal development. The crystal structure of the N-terminus of TBC1D23 shows that its rhodanase domain is catalytically inactive and positioned close to the adjacent TBC domain, which together provide a binding interface for golgin-97/245. This interaction is … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. …

WebMar 21, 2024 · Summary. Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal … WebAug 3, 2024 · Zinc-finger proteins, a superfamily of proteins with a typical structural domain that coordinates a zinc ion and binds nucleic acids, participate in the regulation of growth, development, and stress adaptation in plants. Most zinc fingers are C2H2-type or CCCC-type, named after the configuration of cysteine (C) and histidine (H); the less ...

WebCUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. [5] [6] CDCP1 has also been designated as CD318 ( cluster of … www.ncbi.nlm.nih.gov

WebMar 21, 2024 · GeneCards Summary for NOTCH1 Gene. NOTCH1 (Notch Receptor 1) is a Protein Coding gene. Diseases associated with NOTCH1 include Aortic Valve Disease 1 and Adams-Oliver Syndrome 5 . Among its related pathways are Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants and Pre-NOTCH Expression and Processing .

WebNLRP3. NLR family pyrin domain containing 3 (NLRP3) (previously known as NACHT, LRR and PYD domains-containing protein 3 [NALP3] and cryopyrin), is a protein that in humans is encoded by the NLRP3 gene [5] located on the long arm of chromosome 1. [6] NLRP3 is expressed predominantly in macrophages and as a component of the … grand turks caicosWebFunctional diverse modular proteins share a conserved domain of about 90 amino acids in their C-terminal cysteine-rich region, ... Xenopus mucin B.1 which contains a CCP … chinese silver opium containers with spoonsWebDec 1, 2013 · 4NT5. PubMed Abstract: The C-terminal cystine knot (CK) (CTCK) domain in von Willebrand factor (VWF) mediates dimerization of proVWF in the endoplasmic reticulum and is essential for long multimers required for hemostatic function. The CTCK dimer crystal structure reveals highly elongated monomers with 2 β-ribbons and 4 intra-chain disulfides ... grand turks getaway black paparazziWebThe SAM domain that spreads over around 70 residues is found in diverse eukaryotic organisms. SAM domains have been shown to homo- and hetero-oligomerise, forming multiple self-association architectures and also binding to various non-SAM domain-containing proteins, nevertheless with a low affinity constant. grand turks cruise portWebMar 20, 2014 · All contain sequence signatures for the long β-strands present in CTCK, all contain C5 and C6 in β5 that form the reciprocal inter-chain disulfides, all have C2 and … grand turks getaway blackWebMar 20, 2014 · CTCK domains were called C-terminal or CT domains by Bork, 10 who found them at the C termini of the CCN (cysteine-rich 61, connective tissue growth … chinese silver dollars worthWebJul 12, 2012 · The CTCK domain. The CTCK dimer forms a tee-shaped base for the dimeric bouquet (Figure 4D). The long axes of the 2 VWF CTCK domain monomers are … chinese silvergrass miscanthus sinensis