Rbm3 function
WebAug 4, 2024 · Several findings suggest that RBM3 has morphoregulatory functions germane to its roles in these contexts. For example, RBM3 helps maintain the morphological … WebMar 21, 2024 · Molecular function for RBM3 Gene according to UniProtKB/Swiss-Prot Cold-inducible mRNA binding protein that enhances global protein synthesis at both …
Rbm3 function
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WebJun 27, 2016 · RBM3 plays certain functions such as anti-apoptotic, cell proliferation enhancement, and a proto-oncogene function. Furthermore, Hypothermia-induced neuroprotection up- regulates RBM3 in neuronal ... WebRBM3 is a highly conserved protein engaged in the biosynthesis of different RNA species [including microRNAs (26)], and it is believed to function as a proto-oncogene associated …
WebRNA-binding motif protein 3 (RBM3) is an RNA and DNA-binding protein that in response to various types of cellular functions, such as cell cycle regulation, invasion. 26 Recent studies showed that RBM3 could play critical roles in tumor progression. WebNX_P98179 - RBM3 - RNA-binding protein 3 - Localization. Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation …
WebSep 4, 2024 · RBM3 interacts with IGF2 mRNA binding protein 2 (IMP2), elevates its expression and thereby stimulates IGF2 release in SGZ but not SVZ-NSPCs. ... a major hippocampal function 41, ... WebThe function of RBM3 as a RNA stabilizing agent is cold-inducible, hence referring to the RNA-binding protein as a “cold-shock” protein. RBM3 expression is elevated in response …
WebIn different types of cancer, RBM3 is up regulated and correlated with favourable clinic- pathological features. RBM3 plays certain functions such as anti-apoptotic, cell …
WebMeanwhile, RBM3 has multiple physiological functions and participates in the regulation of various cellular physiological processes, such as antiapoptosis, circadian rhythm, cell … portland or vacation rentalsWebDec 10, 2024 · The cellular functions and biological activities of RBM3 and CIRP appear to be numerous and remain largely unknown. Both RBM3 and CIRP have the capacity to bind RNA and seem to play a key role in post-transcriptional RNA modulation and translation in order to enhance global protein synthesis under stressful cellular conditions . portland or utilityWebNov 27, 2024 · Hydrogen bond, pi–pi and pi–cation are the key interactions between the RNA and the RRM domain. NMR, size exclusion chromatography and chemical cross-linking experiments show that RBM3 forms oligomers in solution, which is favoured by decrease in temperature, thus, potentially linking it to its function as a cold-shock protein. portland or valentine\\u0027s dayWebTogether, RBM3 is a critical factor providing cellular survival advantages in an adverse microenvironment presumably by restoring translation efficacy. ... stability, function, … optimal savings rateWebNX_P98179 - RBM3 - RNA-binding protein 3 - Function. Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic … optimal sacred heartWebSep 2, 2024 · As a sensitive cold-shock protein, RNA binding protein motif 3 (RBM3) exhibits a neuroprotective function in the condition of brain injury. However, how RBM3 is involved in acute ischemic stroke by affecting stress granules (SGs) remains unclear. optimal satcom and pac newsWebThis gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition moti f (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms ... portland or upcoming concerts