WebJun 9, 2024 · SMARCE1-deficient cells, which are a model for clear cell meningioma, are sensitive to ncBAF complex inhibition. WebSMARCE1 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. The protein encoded by this gene is part of the large ATP …
Entry - *603111 - SWI/SNF-RELATED, MATRIX-ASSOCIATED, …
WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity … Websmarce1 mutants have a defective endocardium and an increased expression of cardiac transcription factors in zebrash Jorge Castillo-Robles1, Laura Ramrez 1, Herman P. Spaink 2 & Hilda Lomel 1 gps wilhelmshaven personalabteilung
SMARCE1 deficiency generates a targetable mSWI/SNF …
WebSMARCE1 drives invasion by serving as a master regulator of genes encoding proinvasive ECM and proteases required to degrade basement membrane. In functional studies in 3D cultures and animal models, SMARCE1 is dispensable for tumor growth but is required for the invasive and metastatic progression of cancers. WebMar 21, 2024 · SMARCE1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily E, Member 1) is a Protein Coding gene. Diseases associated with SMARCE1 include Meningioma, Familial and Coffin-Siris Syndrome 5. Among its related … WebAug 5, 2016 · SMARCE1 knockdown reduces lung metastasis of breast cancer in vivo. a Expression levels of SMARCE1 mRNA and protein in LM-EV and LM-SMARCE1-KD cells.b Effect of SMARCE1 knockdown on the growth of xenografts in the fourth inguinal mammary fat pads of female NSG mice.c Spontaneous lung metastasis from orthotopic sites. … gps wilhelmshaven